2 minute read
What It Is
Oxbryta (voxelotor) is a medication used to treat sickle cell disease but recent reports have linked it to serious cardiovascular issues—including sudden cardiac death. Lawsuits are now being investigated for failure to warn about these risks.
What the Recall or Product Is
Approved in 2019, Oxbryta is manufactured by Global Blood Therapeutics Though it increases hemoglobin, it may also pose serious heart risks—especially in children and young adults.
What the Signature Injury Is and How It’s Hurting People
A key injury is liver toxicity. Oxbryta is processed in the liver and can cause elevations in liver enzymes, particularly: ALT (alanine aminotransferase) and AST (aspartate aminotransferase). Elevated levels of these enzymes can be a sign of inflammation or damage to liver cells.
Reported side effects include:
* Arrhythmias and heart palpitations
* Cardiac arrest
* Death during treatment
* Off-label use in younger patients without warning
These consequences are devastating for families and raise concerns about the drug’s safety profile.
Contact Us
If you or a loved one has experienced harm from taking Oxbryta medication, legal options may be available. Call Michael Brady Lynch Firm at 888-585-5970 or email brandon@mblynchfirm.com for a free consultation.
Date: June 03, 2025
Attorney and Editor-In-Chief: Brandon Salter
Editors: Connor Wright, Kali McElroy, and Madison Hurley
Citations:
https://www.pfizer.com/news/press-release/press-release-detail/pfizer-voluntarily-withdraws-all-lots-sickle-cell-disease
https://www.reuters.com/business/healthcare-pharmaceuticals/pfizer-withdraws-sickle-cell-disease-treatment-all-markets-2024-09-25/
https://pharmaceutical-journal.com/article/news/manufacturer-withdraws-treatment-for-sickle-cell-disease-following-concern-over-deaths
https://www.reuters.com/business/healthcare-pharmaceuticals/pfizer-withdraws-sickle-cell-disease-treatment-all-markets-2024-09-25/
https://www.biospace.com/business/pfizer-takes-sickle-cell-drug-oxbryta-off-global-market-cites-risk-of-death